Can Gum Treatment Improve Oral Health in Older Adults with Type 2 Diabetes?
An RCT finds a periodontal health programme improves oral hygiene and knowledge in older diabetic patients, but not oral-health quality of life. PICO summary and commentary.
Hormone Insight Editorial Team
Clinical archive
What Affects Gum Treatment Success in Diabetes?
A machine-learning analysis finds lower baseline periodontal severity and HbA1c predict better response to gum therapy in diabetes (random forest AUC 0.83). PICO summary and commentary.
Does Dapagliflozin Improve Heart Outcomes After a Heart Attack?
A DAPA-MI subanalysis finds dapagliflozin reduces new-onset diabetes after heart attack regardless of glucose or BMI, with most symptom benefit in prediabetes. PICO summary and commentary.
Can CBT for Diet Improve Glucose and Pregnancy Outcomes in Gestational Diabetes?
A multicentre RCT finds a CBT-based dietary app improves postprandial glucose and reduces macrosomia in gestational diabetes. PICO summary and commentary.
Can Home Exercise Improve Brain Function and Inflammation in Diabetic Postmenopausal Women?
An RCT finds home dual-task exercise improves executive function and HDL in diabetic postmenopausal women, but does not change the TNF/IL-10 balance or glucose. PICO summary and commentary.
Does Tirzepatide Improve Insulin Function in People With Obesity?
A SURMOUNT-1 analysis finds tirzepatide improves insulin sensitivity (mostly via weight loss) and beta-cell function (mostly drug-driven) in obesity without diabetes. PICO summary and commentary.
Intensive Blood Pressure Control in Diabetes With Prior Stroke: An ACCORD-BP Post-Hoc Analysis
A post-hoc analysis of 307 ACCORD-BP participants with type 2 diabetes and prior stroke links intensive systolic blood pressure control to fewer cardiovascular events. PICO summary and expert commentary.