Hormone Insight Editorial Team
Clinical archive
Does Early Weight Loss Predict Long-Term Results with Tirzepatide?
A SURMOUNT-1 analysis finds 90% of early non-responders to tirzepatide still reached 5% weight loss by week 72, supporting extending treatment. PICO summary and commentary.
Can Galician Olive Oil Help Control Blood Sugar?
A 24-week trial finds high-phenolic olive oil reduces insulin resistance in type 2 diabetes, but without changing lipids or blood pressure. PICO summary and commentary.
Does the Omnipod 5 Activity Feature Help Control Blood Sugar During Exercise?
A crossover trial finds the Omnipod 5 Activity feature reduces insulin and blunts exercise glucose drops in type 1 diabetes, though hypoglycemia rates were unchanged. PICO summary and commentary.
Is Nanocurcumin Safe and Effective for Diabetic Nerve Pain?
A double-blind RCT finds nanocurcumin does not improve pain or neuropathy outcomes in diabetic peripheral neuropathy. PICO summary and expert commentary.
Does Slower Semaglutide Titration Improve Tolerability and Adherence?
A randomized open-label pilot trial tested whether slower, flexible semaglutide titration reduces gastrointestinal dropout in type 2 diabetes versus the label regimen. PICO summary and expert commentary.
Can mHealth Improve Communication Between Patients and Providers?
A secondary analysis of the DIAMANTE trial finds an adaptive texting intervention did not improve patient-provider communication in diabetes and depression. PICO summary and commentary.
Letrozole vs Programmed FET in PCOS: No Difference in Pregnancy Rates
A small open-label RCT found no significant difference in clinical pregnancy rates between letrozole ovulation and programmed endometrial preparation for frozen embryo transfer in women with PCOS, with letrozole needing simpler luteal support. PICO summary and expert commentary.
