Summary: In Chinese middle-aged and elderly adults with prediabetes or early diabetes, purified anthocyanin supplementation (160, 320, and 640 mg/day…
Browsing: Nutrition & Lifestyle
Diet, physical activity, behavioural and lifestyle interventions for metabolic and endocrine health.
A secondary analysis of the Minnesota Green Tea Trial finds high-dose green tea extract does not reduce inflammatory markers in overweight postmenopausal women, a robust null result. PICO summary and commentary.
A 12-week dose-response trial finds purified anthocyanin supplements up to 640 mg/day do not improve arterial stiffness, blood pressure, or cardiovascular risk in older adults with high blood sugar. PICO summary and commentary.
An RCT finds seated exercise gives greater pain relief, knee function, and physical quality of life than standing exercise in obese women with knee osteoarthritis, while standing favours mental quality of life. PICO summary and commentary.
A 6-month open-label RCT finds adding a Mediterranean diet and nutritional supplements to dapagliflozin improves glycaemia, albuminuria, nutrition, and quality of life more than dapagliflozin alone in diabetic nephropathy. PICO summary and commentary.
An RCT finds combining HIIT with asparagus root extract improves oxidative, inflammatory, and lipid markers in overweight young adults, while the extract alone raises a pro-oxidant marker. PICO summary and commentary.
A 24-week RCT finds neither a low-carbohydrate nor a Mediterranean diet significantly changes bone turnover markers in young people with type 1 diabetes, an exploratory null result. PICO summary and commentary.
Summary: In older adults at risk for type 2 diabetes, resistance exercise training significantly improved targeted cognitive function compared to…
Summary: In adults with prediabetes, metformin combined with aerobic exercise significantly improved skeletal muscle tissue characteristics and metabolic markers compared…
A small 12-week MRI trial finds aerobic exercise improves muscle composition and achieves normoglycaemia in 80-90% of prediabetic adults versus 20% with metformin, with combination adding visceral-fat and muscle-size benefit. PICO summary and commentary.