A small RCT finds flaxseed oil reduces platelet aggregability but not other risk markers in type 2 diabetes, with no ApoE genotype effect. PICO summary and expert commentary.
Browsing: Nutrition & Lifestyle
Diet, physical activity, behavioural and lifestyle interventions for metabolic and endocrine health.
A feasibility analysis finds a culturally tailored dietary intervention engages diverse women with gestational diabetes equally, but does not change measured intake. PICO summary and commentary.
A secondary analysis of the BEFORE THE BEGINNING trial finds preconception lifestyle change does not reduce macrosomia or neonatal adiposity. PICO summary and expert commentary.
The Look AHEAD trial demonstrated that intensive lifestyle intervention targeting weight loss in overweight or obese adults with type 2 diabetes did not reduce cardiovascular events over 9.6 years despite clear differences in weight, fitness, and glycaemic control, establishing a critical negative result that informed the rationale for pharmacological obesity treatment with greater weight loss efficacy.
A four-arm RCT finds combining training with a polyphenol supplement improves prediabetes markers most, with exercise the main driver. PICO summary and expert commentary.
An RCT finds the AntiAGE-Biom probiotic does not lower HbA1c but shows a subgroup body-composition signal in type 2 diabetes. PICO summary and expert commentary.
An RCT finds Chester Step Test-guided post-dinner exercise lowers postprandial glucose and variability in type 2 diabetes on exercise days. PICO summary and expert commentary.
A recruitment analysis finds men, Hispanics, and Spanish speakers underenrol at every step of a diabetes exercise trial despite active outreach. PICO summary and commentary.
A secondary analysis finds beetroot supplements improve fatty acid and oxidant markers in coronary artery disease, but only short-term surrogates. PICO summary and commentary.
An RCT finds exogenous ketone salts produce no body-composition advantage over placebo on a hypocaloric diet. PICO summary and expert commentary.