Summary: In adults with obesity and/or type 2 diabetes (mean age 47.9 years, 74% female) referred for physical activity intervention,…
Browsing: Type 2 Diabetes
Landmark trials and recent evidence on type 2 diabetes management, glucose-lowering therapy, and outcomes.
A 12-week RCT finds structured yoga improves fasting glucose, HbA1c, and self-care in low-income women with type 2 diabetes, though the glycaemic effect exceeds typical yoga trials. PICO summary and commentary.
A small biomarker RCT finds empagliflozin reduces the renal tubular marker KIM-1 in diabetic heart failure with preserved ejection fraction, with no effect on other biomarkers. PICO summary and commentary.
A small RCT finds adding sitagliptin or bedtime NPH insulin lowers HbA1c similarly in type 2 diabetes but produces distinct microRNA changes, with sitagliptin affecting a broader set. PICO summary and commentary.
A 20-week RCT finds adding empagliflozin improves glucose, kidney function, neuropathy symptoms, and nerve conduction velocity in type 2 diabetes, though amplitude and exam scores were unchanged. PICO summary and commentary.
A 12-week RCT finds adding sitagliptin to metformin improves fasting glucose, lipids, beta-cell function, and inflammatory cytokines, though HbA1c did not change significantly. PICO summary and commentary.
A subgroup analysis finds adding Control-IQ+ automated insulin delivery to GLP-1 agonist therapy lowers HbA1c and improves time in range without weight gain in insulin-treated type 2 diabetes. PICO summary and commentary.
Summary: In patients with type 2 diabetes mellitus accompanied by cognitive decline, Huayu Tongluo moxibustion therapy targeting specific acupuncture points…
A single-blind RCT finds personalised exercise prescribed from the Chester Step Test reduces glycaemic variability in type 2 diabetes under free-living conditions. PICO summary and commentary.
Summary: In patients with diabetes or prediabetes identified through electronic health records (EHR) recruitment, invitation and recruitment into a physical…
