Clinical evidence summaries for type 2 diabetes, including glycaemic therapies, cardiovascular outcomes, kidney protection, complications, technology, obesity, and long-term safety.
An RCT finds five weeks of aquatic exercise improves blood pressure and fitness within-group in type 2 diabetes, but shows no advantage over control. PICO summary and commentary.
An RCT finds low-dose dexmedetomidine steadies perioperative glucose in diabetic surgery while higher doses worsen it. PICO summary and expert commentary for clinicians.
An RCT finds interdisciplinary care with family empowerment improves blood pressure, glucose, and quality of life in comorbid hypertension and diabetes. PICO summary and commentary.
A translational study finds rhPTH(1-34) outperforms alendronate for bone density in diabetic osteoporosis, a low-turnover state. PICO summary and expert commentary for clinicians.
A 12-month RCT finds curcumin 1500 mg daily reduces liver fat, stiffness, and HbA1c in obese type 2 diabetes with MASLD. PICO summary and expert commentary for clinicians.
An RCT secondary analysis finds probiotics plus omega-3 do not significantly improve beta-cell function versus placebo in type 2 diabetes. PICO summary and expert commentary.
The SLowDOWN phase III RCT finds sitagliptin preserves hip bone density in women with type 2 diabetes. PICO summary and expert commentary for clinicians.
A small RCT finds flaxseed oil reduces platelet aggregability but not other risk markers in type 2 diabetes, with no ApoE genotype effect. PICO summary and expert commentary.
A crossover RCT finds a specific probiotic strain modestly improves fasting glycaemia and beta-cell indices in metformin-treated type 2 diabetes. PICO summary and expert commentary.
A pilot RCT finds a culturally tailored WeChat-delivered programme improves self-efficacy and reduces diabetes distress in Chinese Americans with type 2 diabetes. PICO summary and commentary.
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