A double-blind RCT finds empagliflozin gives broader cardiometabolic benefit than sitagliptin or metformin as add-on therapy in type 2 diabetes. PICO summary and commentary.
Browsing: Type 2 Diabetes
Clinical evidence summaries for type 2 diabetes, including glycaemic therapies, cardiovascular outcomes, kidney protection, complications, technology, obesity, and long-term safety.
An RCT finds a periodontal health programme improves oral hygiene and knowledge in older diabetic patients, but not oral-health quality of life. PICO summary and commentary.
A machine-learning analysis finds lower baseline periodontal severity and HbA1c predict better response to gum therapy in diabetes (random forest AUC 0.83). PICO summary and commentary.
A post-hoc analysis of 307 ACCORD-BP participants with type 2 diabetes and prior stroke links intensive systolic blood pressure control to fewer cardiovascular events. PICO summary and expert commentary.
A 24-week trial finds high-phenolic olive oil reduces insulin resistance in type 2 diabetes, but without changing lipids or blood pressure. PICO summary and commentary.
A randomized open-label pilot trial tested whether slower, flexible semaglutide titration reduces gastrointestinal dropout in type 2 diabetes versus the label regimen. PICO summary and expert commentary.
Summary: In individuals with type 2 diabetes, cinnamon supplementation significantly reduced anthropometric measurements compared to placebo, though it was not…
A mechanistic randomized trial found empagliflozin reduced total-body norepinephrine turnover at 1 day and 12 weeks even as hepatic glucose production rose, with the two changes inversely correlated. PICO summary and expert commentary.
Summary: In type 2 diabetic stage-II periodontitis patients, non-surgical periodontal therapy with adjunctive hyaluronic acid (HA) gel significantly improved periodontal…
“`html Summary: In patients with type 2 diabetes mellitus, a combined exercise program significantly reduced abdominal fat and improved sleep…