A single-centre Korean pilot RCT of a physician-led digital education and remote-monitoring platform in type 2 diabetes, where both arms reached the same 3-month HbA1c and the early gain reversed once monitoring stopped. PICO summary and expert commentary.
Browsing: Diabetes
Evidence summaries and landmark trials across type 1, type 2, prevention, glycaemic control, complications, and diabetes technology.
A pooled analysis of three finerenone trials found a modest reduction in new-onset atrial fibrillation/flutter across the cardio-kidney-metabolic spectrum. PICO summary and expert commentary.
A qualitative substudy of 10 youth with type 1 diabetes and high HbA1c describing their lived experience of starting advanced hybrid closed-loop therapy. PICO summary and expert commentary.
A TrialNet post hoc analysis in 40 high-risk relatives found oral insulin favourably shifted a combined glucose and C-peptide surrogate (p=0.037), not a proven delay in diabetes onset. PICO summary and expert commentary.
A small secondary analysis of the EDICT randomised trial reports that initial triple therapy was associated with slower carotid intima-media thickness progression and lower liver fat than sequential add-on therapy at matched glycaemic control. PICO summary and expert commentary.
A small single-centre randomised trial testing whether a mobile educational platform improves glycaemic control and adherence in steroid-induced diabetes. PICO summary and expert commentary.
Summary: In a post hoc analysis of three clinical trials spanning the glucose tolerance spectrum, fasting and 1-hour circulating Gremlin…
A 4-arm randomised trial in older adults with prediabetes found HIIT improved peripheral but not whole-body insulin sensitivity, with walking showing the opposite pattern. PICO summary and expert commentary.
The ROBUST study protocol describes a planned randomized trial of a social network-enhanced lifestyle intervention for obesity in Black and Hispanic adults, with no outcome results yet. PICO summary and expert commentary.
A 96-patient randomised controlled trial of manufacturer-developed autologous platelet gel versus standard dressings for chronic neuropathic diabetic foot ulcers, with PICO summary and expert commentary.