Summary: In adults (n=117) with coronary artery stenosis located proximal to a myocardial bridge requiring percutaneous coronary intervention, IVUS-guided stent…
Browsing: Cardiovascular Outcomes
An RCT finds intraoperative dexmedetomidine reduces glucose variability, insulin requirements, and CRP in diabetic off-pump CABG patients, though endpoints are surrogate. PICO summary and commentary.
A prespecified BRIGHT-4 subgroup analysis finds bivalirudin reduces death or major bleeding versus heparin in lower-BMI STEMI patients but not higher-BMI, with a significant interaction. PICO summary and commentary.
A small RCT finds a 12-week hybrid Tai Chi cardiac rehab programme reduces perceived stress and oxidised LDL more than conventional exercise in chronic coronary syndrome. PICO summary and commentary.
An OPTION post-hoc analysis finds indobufen-based antiplatelet therapy after stenting performs consistently regardless of diabetes status, with a similar bleeding advantage. PICO summary and commentary.
Summary: In adults with uncontrolled type 2 diabetes in China, a mobile app-based intervention significantly improved HbA1c and systolic blood…
The 4-year DAPAHEART follow-up finds dapagliflozin raises coronary flow reserve by 34% and reduces epicardial fat, apparently independent of weight loss. PICO summary and commentary.
An RCT finds triple therapy with a statin, SGLT2 inhibitor, and PCSK9 inhibitor lowers lipids more than monotherapy in ischemic heart disease. PICO summary and commentary.
📚 Part of the GLP-1 Receptor Agonists Trial Guide — every landmark trial in one place. Clinical Context GLP-1 receptor…
Clinical Context Curcumin, the principal bioactive compound in turmeric (Curcuma longa), has been studied extensively for anti-inflammatory, antioxidant, and metabolic…