Hormone Insight Editorial Team
Clinical archive
Does Lower-Limb Resistance Training Help Diabetic Foot Ulcers?
An RCT finds lower-limb resistance training improves glycaemic control and quality of life in diabetic foot ulcer patients, but not wound healing. PICO summary and commentary.
rhTSH Non-Inferior to Thyroid Hormone Withdrawal for Radioactive Iodine Ablation in Intermediate-Risk Thyroid Cancer: RCT
A phase 3 trial finds recombinant human TSH non-inferior to thyroid hormone withdrawal for radioiodine ablation in intermediate-risk thyroid cancer, with fewer adverse events. PICO summary and commentary.
rhTSH Noninferior to Hormone Withdrawal for RAI Ablation in Intermediate-Risk Thyroid Cancer
An open-label phase 3 noninferiority trial finds recombinant human thyrotropin matches thyroid hormone withdrawal for radioactive iodine ablation success in intermediate-risk differentiated thyroid cancer, with fewer adverse events. PICO summary and expert commentary.
Prolonged Sleep Restriction Reduces TSH Levels in Healthy Women: Pooled RCT Analysis
Pooled RCTs find mild sleep restriction lowers TSH in women specifically, with no effect overall and no change in FT4. PICO summary and expert commentary.
Cotadutide and Albuminuria in Diabetic Kidney Disease: A Phase 2b Trial
A phase 2b randomized trial found that cotadutide reduced urinary albumin-to-creatinine ratio versus placebo in type 2 diabetes with chronic kidney disease, a surrogate signal requiring confirmation. PICO summary and expert commentary.