A phase I/II randomized trial found long-term controlled-release oral GABA (Remygen) did not improve C-peptide, CGM metrics, or HbA1c in men with long-standing type 1 diabetes, and side effects were common. PICO summary and expert commentary.
A single-centre randomised trial of 200 women found metformin matched insulin for glycaemic control in gestational diabetes, with some neonatal outcomes favouring metformin. PICO summary and expert commentary.
A three-arm randomized trial in Texans with uncontrolled type 2 diabetes found that all three self-paced virtual and technology-based self-management programs significantly reduced A1c, with no in-person comparator. PICO summary and expert commentary.
A Hong Kong cluster RCT found point-of-care capillary HbA1c screening doubled uptake and detected more type 2 diabetes than venous HbA1c testing in at-risk primary care patients. PICO summary and expert commentary.
A small community-based controlled study in northeastern Thailand found a health literacy and self-management education program raised health literacy and exercise behaviour, with no glycaemic outcome reported. PICO summary and expert commentary.
A single-centre Shanghai RCT found a family-support self-management programme raised self-management behaviour scores in type 2 diabetes, while HbA1c and other biochemical markers did not improve significantly. PICO summary and expert commentary.
A secondary analysis of the CORDIOPREV trial reports that a lower baseline neutrophil count is associated with type 2 diabetes remission in patients with coronary heart disease following a Mediterranean diet. PICO summary and expert commentary.
A within-trial economic evaluation of the CIC-PDD integrated care model for type 2 diabetes with depressive symptoms reports a cost per QALY around $7,400 to $7,900. PICO summary and expert commentary.
A randomized crossover trial in 75 young adults found acute sucralose raised hypothalamic blood flow and, versus sucrose, increased hunger, with no hunger difference versus water. PICO summary and expert commentary.
DIAMONDS is a published protocol for a randomised trial testing a supported diabetes self-management programme in adults with type 2 diabetes and severe mental illness; no results are reported yet. PICO summary and expert commentary.
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