A 92-patient randomized trial in Taiwan tested whether 6-month health coaching improves eGFR in type 2 diabetes with early-stage CKD. PICO summary and expert commentary.
Browsing: PICO
An exploratory plasma proteomic analysis of the Phase 2b MOSAIC trial maps selonsertib activity to fibrosis, inflammation and oxidative-stress pathways in diabetic kidney disease, with PICO summary and expert commentary.
A prespecified FIGARO-DKD subgroup analysis of 325 Chinese adults with type 2 diabetes and CKD found a significant reduction in the secondary kidney outcome with finerenone but no significant cardiovascular benefit. PICO summary and expert commentary.
A small open-label RCT testing whether real-time CGM feedback added to individualized nutrition therapy improves diet and sleep in prediabetes with overweight or obesity. PICO summary and expert commentary.
A 2×2 cluster RCT in 284 adults with type 2 diabetes and overweight or obesity testing whether nudge-based dietary education and tableware lower HbA1c. PICO summary and expert commentary.
A small randomized trial of CGM-guided insulin titration in cardiac surgery patients with type 2 diabetes and prediabetes missed its primary time-in-range endpoint but improved several secondary glucose metrics. PICO summary and expert commentary.
A small single-site quasi-experimental study tested whether an Information-Motivation-Behavioral Skills education programme raises medication adherence in older adults with type 2 diabetes. PICO summary and expert commentary.
A randomized controlled trial found progestin-primed ovarian stimulation and the GnRH antagonist protocol produced statistically similar euploidy rates in PGT-A cycles. PICO summary and expert commentary.
An unblinded randomized trial testing whether adding the Vitadio self-management app to standard care improves HbA1c in type 2 diabetes. PICO summary and expert commentary.
A single-centre, open-label randomised trial of empagliflozin 10 mg in 70 patients with type 2 diabetes and HFpEF found improved 6-minute walk distance and diastolic reserve markers. PICO summary and expert commentary.