A secondary analysis of the BEFORE THE BEGINNING trial finds a preconception lifestyle intervention does not significantly reduce large birth weight or change neonatal body composition. PICO summary and commentary.
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A small RCT finds a digital-twin decision-support system with a simulation-assisted bolus calculator improves time in range and reduces hypoglycaemia in type 1 diabetes. PICO summary and commentary.
Summary: In adults with infected diabetic foot ulcers requiring microbiological sampling, tissue sampling to identify causative pathogens through biopsy or…
Summary: In adults diagnosed with type 2 diabetes mellitus (n=62), cognitive motor dual-task blindfold training (CMDBT) combined with moderate-intensity aerobic…
Summary: In community-dwelling adults with type 2 diabetes mellitus (n=120) stratified by clinical risk level, a three-tiered linkage management model…
A 12-week RCT finds adding cognitive-motor dual-task blindfold training to exercise improves cognitive scores more than exercise alone in type 2 diabetes. PICO summary and commentary.
An ASCOT analysis finds high blood pressure variability is strongly linked to worse cardiovascular and renal outcomes in diabetes, with amlodipine-based therapy reducing events partly via lower variability. PICO summary and commentary.
A 2-year RCT follow-up finds Tai Chi preserves cognition and executive/visuospatial function in older adults with diabetes and mild cognitive impairment, beating health education and walking. PICO summary and commentary.
A small open-label RCT finds early NPH insulin plus infusion speeds resolution of severe DKA and delays rebound hyperglycaemia, without a significant difference in hypoglycaemia. PICO summary and commentary.
Clinical Context Gestational diabetes mellitus (GDM) affects 6-9% of pregnancies globally and is associated with significant maternal and fetal complications.…