A randomised controlled trial of a psychosocial weight-management programme in overweight or obese pregnant women improved diet and activity but not gestational diabetes, preeclampsia, or caesarean rates. PICO summary and expert commentary.
Browsing: PICO
Structured PICO summaries for doctors and healthcare professionals, covering population, intervention, comparison, outcomes, expert commentary, and references across diabetes, endocrinology, obesity, and cardiometabolic medicine.
A multicentre randomised trial testing a CBT-based WeChat dietary programme against standard care for postprandial glucose and pregnancy outcomes in gestational diabetes. PICO summary and expert commentary.
An EXSCEL post hoc simulation and mediation analysis showing conventional risk-factor changes explain only a modest share of once-weekly exenatide’s cardiovascular effects. PICO summary and expert commentary.
A Brazilian randomized community trial reports preliminary reach and adherence for group-based nutrition interventions in primary care obesity management. PICO summary and expert commentary.
A secondary analysis of a 12-month randomized trial found 4:3 intermittent fasting improved binge and uncontrolled eating versus daily calorie restriction, with no difference in appetite hormones. PICO summary and expert commentary.
A 6-month randomized sub-analysis found that a multicomponent weight-loss program shifted gut microbiota and linked Faecalibacterium abundance to fat-mass loss, though causation was not established. PICO summary and expert commentary.
A small non-randomised secondary analysis comparing home- and gym-based exercise in older adults with obesity during COVID-19 lockdowns, with PICO summary and expert commentary.
A manufacturer-sponsored secondary analysis found a digital diabetes logbook nearly doubled the odds of reaching HbA1c 6.5% or below at 3 months, with associated real-world glucose reductions. PICO summary and expert commentary.
A 30-participant pilot randomised trial of an 8-week intensive exercise protocol versus diet plus brisk walking in young adults with obesity, with PICO summary and expert commentary.
A post-hoc analysis of the SPRINT trial finds a higher triglyceride-glucose index is associated with greater cardiovascular risk in controlled hypertension, significant only under standard blood pressure treatment. PICO summary and expert commentary.