A randomised comparison finds gadobutrol non-inferior to meglumine gadoterate for pituitary DCE-MRI but with a higher Kep to recognise, not a clear superiority. PICO summary and commentary.
Browsing: PICO
Structured PICO summaries for doctors and healthcare professionals, covering population, intervention, comparison, outcomes, expert commentary, and references across diabetes, endocrinology, obesity, and cardiometabolic medicine.
A post-hoc ACCORD-BP analysis links intensive blood pressure control to lower cardiovascular events in diabetics with prior stroke, without raising recurrent stroke. PICO summary and commentary.
An RCT finds the Diabetes Conversation Map improves knowledge, self-management, and self-efficacy in type 2 diabetes, though without clinical endpoints. PICO summary and commentary.
A non-inferiority trial finds once-daily prolonged-release pregabalin relieves diabetic nerve pain as well as immediate-release, offering simpler dosing. PICO summary and commentary.
An open-label multicentre RCT in 155 women with PCOS found that a letrozole ovulation regimen for frozen-thawed embryo transfer achieved clinical pregnancy rates comparable to a programmed regimen while requiring simpler luteal support. PICO summary and expert commentary.
A triple-blind RCT finds cinnamon supplementation does not significantly reduce weight or BMI in type 2 diabetes. PICO summary and expert commentary.
A single-centre Egyptian RCT testing whether adding Islamic intermittent fasting to lifestyle modification improves metabolic syndrome markers, with PICO summary and expert commentary.
A small RCT finds hyaluronic acid adds no periodontal benefit over mechanical cleaning in diabetic periodontitis, though HbA1c fell only in the HA group. PICO summary and commentary.
A four-arm trial finds combination aerobic-resistance exercise is the only programme to improve objective sleep in type 2 diabetes, alongside abdominal fat loss. PICO summary and commentary.
A crossover trial finds almond milk offers no glycaemic advantage over carbohydrate-matched cow milk in type 2 diabetes. PICO summary and expert commentary.