Does Curcumin Help with Blood Sugar and Gut Health in Prediabetic Seniors?
A small pilot finds curcumin lowers HbA1c in prediabetic older adults, but without changing weight, lipids, or overall gut microbiome diversity. PICO summary and commentary.
Nutrition & Lifestyle
Diet, physical activity, behavioural and lifestyle interventions for metabolic and endocrine health.
Multifactorial Care in Type 2 Diabetes: A Single-Centre RCT
A single-centre randomised controlled trial testing multidisciplinary multifactorial care against standard care in 192 adults with type 2 diabetes, with a modest HbA1c reduction and improved eGFR. PICO summary and expert commentary.
Does Orange Juice Spike Blood Sugar at Breakfast in Type 2 Diabetes?
A crossover trial finds orange juice with breakfast raises glucose no more than whole orange or a sugary drink of matched sugar in well-controlled type 2 diabetes. PICO summary and commentary.
Do Mixed Nuts Improve Cholesterol in Older Overweight Adults?
A randomised crossover trial found 60 g/day of mixed nuts for 16 weeks lowered apolipoprotein B and VLDL and LDL particle numbers in older adults with overweight or obesity. PICO summary and expert commentary.
Does Pharmacist-Led Collaborative Care Improve Quality of Life in Type 2 Diabetes?
A 1-year randomised controlled trial of pharmacist-led collaborative care versus standard care in 400 adults with type 2 diabetes, reporting EQ-5D and visual analogue scale quality-of-life gains alongside a larger HbA1c reduction. PICO summary and expert commentary.
Does a Family-Centered Empowerment Program Improve Illness Acceptance and Self-Management in Type 2 Diabetes?
A small single-blind RCT testing whether a family-centered empowerment program improves patient-reported illness acceptance and self-management in type 2 diabetes. PICO summary and expert commentary.
Plant-Based Diet in a Predominantly Māori Community: Weight Loss in an RCT, Limited Glycaemic Signal
A 10-week whole-food plant-based community programme produced significant between-group weight loss but no significant glycaemic or lipid change in this small New Zealand RCT. PICO summary and expert commentary.
Isomaltulose Timing Around Exercise in Type 1 Diabetes: A Small Crossover Study
A small randomized crossover study in eight adults with type 1 diabetes on automated insulin delivery found that splitting isomaltulose into smaller servings during exercise produced steadier plasma glucose than a single pre-exercise serving. PICO summary and expert commentary.
Combined Diet and Exercise in Male Athletes With Type 2 Diabetes: A Small 12-Week RCT
A 12-week four-arm randomised trial in 36 male recreational athletes found that combined diet plus exercise improved body composition and glycaemic markers, with small effect sizes. PICO summary and expert commentary.