A 12-month RCT finds daily curcumin reduces liver fat, stiffness, and HbA1c and improves inflammatory and antioxidant markers in obese type 2 diabetes with fatty liver. PICO summary and commentary.
Browsing: Nutrition & Lifestyle
Diet, physical activity, behavioural and lifestyle interventions for metabolic and endocrine health.
An exploratory sub-study finds inflammatory markers fall with weight loss whether by intermittent fasting or calorie restriction, with no fasting-specific advantage. PICO summary and commentary.
Clinical Context Chronic low-grade inflammation is increasingly recognized as a central driver of metabolic disease progression. In obesity and prediabetes,…
An analysis of the overall-negative MIND diet trial finds a cognitive benefit only in older adults with BMI 35 or above, a hypothesis-generating subgroup signal. PICO summary and commentary.
A secondary analysis finds diabetes app users still average only 17 g/day fibre over a year, below target, with no link to HbA1c, suggesting basic app feedback is not enough. PICO summary and commentary.
A small CGM crossover study finds 30 g/day defatted fenugreek flakes reduces 24-hour glucose excursions and variability in type 2 diabetes. PICO summary and commentary.
A secondary analysis finds probiotics plus omega-3 improve beta-cell function only marginally versus baseline and not versus placebo when adjusted, though secondary metabolic markers improve. PICO summary and commentary.
Summary: In trained adult athletes participating in a controlled energy availability study, short-term low energy availability (LEA) at 15 kcal·kg…
Summary: In adults diagnosed with type 2 diabetes receiving standard medical treatment in China, Sanxiao Jiuzhi Gong (SJG) exercise therapy…
A single-centre RCT reports large glycaemic gains from qigong (Sanxiao Jiuzhi Gong) in type 2 diabetes, but the implausibly large effect size warrants caution. PICO summary and commentary.