A small open-label Spanish RCT found a digital education program added to GLP-1 therapy produced greater HbA1c, weight, and adherence gains than usual care over six months. PICO summary and expert commentary.
Browsing: Type 2 Diabetes
Clinical evidence summaries for type 2 diabetes, including glycaemic therapies, cardiovascular outcomes, kidney protection, complications, technology, obesity, and long-term safety.
A small open-label randomised trial comparing dapagliflozin with insulin glargine as a fourth agent for glycaemic variability in type 2 diabetes inadequately controlled on triple therapy. PICO summary and expert commentary.
In 22,220 older US adults, daily vitamin D did not significantly reduce incident type 2 diabetes, though a pooled meta-analysis hinted at a modest benefit. PICO summary and expert commentary.
A three-arm randomized trial in Texans with uncontrolled type 2 diabetes found that all three self-paced virtual and technology-based self-management programs significantly reduced A1c, with no in-person comparator. PICO summary and expert commentary.
A Hong Kong cluster RCT found point-of-care capillary HbA1c screening doubled uptake and detected more type 2 diabetes than venous HbA1c testing in at-risk primary care patients. PICO summary and expert commentary.
A small community-based controlled study in northeastern Thailand found a health literacy and self-management education program raised health literacy and exercise behaviour, with no glycaemic outcome reported. PICO summary and expert commentary.
A single-centre Shanghai RCT found a family-support self-management programme raised self-management behaviour scores in type 2 diabetes, while HbA1c and other biochemical markers did not improve significantly. PICO summary and expert commentary.
A secondary analysis of the CORDIOPREV trial reports that a lower baseline neutrophil count is associated with type 2 diabetes remission in patients with coronary heart disease following a Mediterranean diet. PICO summary and expert commentary.
A within-trial economic evaluation of the CIC-PDD integrated care model for type 2 diabetes with depressive symptoms reports a cost per QALY around $7,400 to $7,900. PICO summary and expert commentary.
DIAMONDS is a published protocol for a randomised trial testing a supported diabetes self-management programme in adults with type 2 diabetes and severe mental illness; no results are reported yet. PICO summary and expert commentary.