A four-arm RCT finds only low-dose dexmedetomidine improves perioperative glucose in type 2 diabetes, while higher doses raise it, showing a dose-dependent effect. PICO summary and commentary.
Browsing: Type 2 Diabetes
Landmark trials and recent evidence on type 2 diabetes management, glucose-lowering therapy, and outcomes.
An RCT finds an eHealth app improves HbA1c at 4 months in older diabetes patients, but usage declines by 8 months, raising durability concerns. PICO summary and commentary.
Summary: In adults diagnosed with type 2 diabetes receiving standard medical treatment in China, Sanxiao Jiuzhi Gong (SJG) exercise therapy…
A single-centre RCT reports large glycaemic gains from qigong (Sanxiao Jiuzhi Gong) in type 2 diabetes, but the implausibly large effect size warrants caution. PICO summary and commentary.
Summary: In patients with type 2 diabetes exhibiting reduced salivary gland function and associated oral symptoms, low-level laser therapy combined…
A very small interim RCT analysis finds laser and TENS to the salivary glands improve flow and shift the oral microbiome in type 2 diabetes, but evidence is preliminary. PICO summary and commentary.
Summary: In patients with type 2 diabetes, stratified by ApoE genotype (E2/E3, E3/E3, E3/E4, and E4/E4 carriers), flaxseed oil supplementation…
An open-label RCT finds 24 g/day fibre cereal improves the FIB-4 fibrosis index and HbA1c in type 2 diabetes with fatty liver, without weight change. PICO summary and commentary.
A 5-week RCT finds aquatic exercise improves blood pressure and function within-group in type 2 diabetes, but without significant differences versus controls. PICO summary and commentary.
An RCT finds higher-temperature (44-46C) moxibustion improves cognition and HbA1c more than lower temperatures in type 2 diabetes, though fasting glucose was unchanged. PICO summary and commentary.