Diabetes and glycaemic-control evidence summaries covering HbA1c, glucose monitoring, medication comparisons, hypoglycaemia, patient-reported outcomes, and clinical interpretation.
A small single-centre randomised trial testing whether a mobile educational platform improves glycaemic control and adherence in steroid-induced diabetes. PICO summary and expert commentary.
A 4-arm randomised trial in older adults with prediabetes found HIIT improved peripheral but not whole-body insulin sensitivity, with walking showing the opposite pattern. PICO summary and expert commentary.
A secondary cost-consequence and budget impact analysis of the TELE-DD trial found a nurse-led telephone program for nonadherent Type 2 diabetics with comorbid depression became cheaper per glycaemically controlled patient by 12-18 months. PICO summary and expert commentary.
A 6-month structured anti-inflammatory diet-and-exercise programme in 542 adults with prediabetes delayed diabetes onset but did not lower 8-year incidence. PICO summary and expert commentary.
A phase 3 open-label trial in 440 Chinese adults found the dulaglutide biosimilar LY05008 met its equivalence margin for HbA1c reduction against reference dulaglutide. PICO summary and expert commentary.
A small open-label Spanish RCT found a digital education program added to GLP-1 therapy produced greater HbA1c, weight, and adherence gains than usual care over six months. PICO summary and expert commentary.
A small open-label randomised trial comparing dapagliflozin with insulin glargine as a fourth agent for glycaemic variability in type 2 diabetes inadequately controlled on triple therapy. PICO summary and expert commentary.
A double-blind RCT in 67 children found Ringer's lactate shortened time to DKA resolution versus 0.9% saline, with less hyperchloraemia. PICO summary and expert commentary.
A phase I/II randomized trial found long-term controlled-release oral GABA (Remygen) did not improve C-peptide, CGM metrics, or HbA1c in men with long-standing type 1 diabetes, and side effects were common. PICO summary and expert commentary.
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