Summary:
In patients with type 2 diabetes mellitus, a ketogenic diet combined with dulaglutide significantly improved glucose and lipid metabolism, reduced insulin resistance, and enhanced sleep quality and overall quality of life compared to dulaglutide treatment alone, though it was associated with no significant reported side effects.
| PICO | Description |
|---|---|
| Population | Adults diagnosed with type 2 diabetes mellitus (n=104), managed in a randomized study setting. |
| Intervention | Combination therapy of dulaglutide plus a ketogenic diet administered for 6 months. |
| Comparison | Treatment with dulaglutide alone without dietary modification. |
| Outcome | The combination therapy led to significantly lower blood glucose and lipid levels (P<0.05), improved insulin sensitivity, reduced insulin resistance, and better sleep quality and quality of life scores at 6-month follow-up compared to the control group. |
Source: Rui Gao, et al. “Effect of ketogenic diet plus dulaglutide on glucose and lipid metabolism in diabetes mellitus.” Read article here.
