Summary:
In elderly patients with type 2 diabetes mellitus (T2DM) suffering from sleep disorders,
resistance exercise combined with metformin treatment significantly improved glycemic stability (lower fasting blood glucose, 2-hour postprandial glucose, and HbA1c) and enhanced sleep quality (better Pittsburgh Sleep Quality Index scores) compared to metformin alone treatment over 12 weeks, though it was associated with moderate muscle soreness and transient fatigue reported in some participants.
| PICO | Description |
|---|---|
| Population | Elderly patients diagnosed with type 2 diabetes mellitus (T2DM) experiencing sleep disorders. |
| Intervention | Combination of resistance exercise program plus metformin treatment administered over 12 weeks. |
| Comparison | Metformin treatment alone, without additional exercise intervention. |
| Outcome | Resistance exercise plus metformin significantly reduced fasting blood glucose, 2-hour postprandial glucose, HbA1c levels, and improved Pittsburgh Sleep Quality Index scores. Some participants reported mild muscle soreness and transient fatigue associated with the exercise regimen. |
Source: Xiang Li, et al. “Effects of resistance exercise combined with metformin on glycemic stability and sleep quality in elderly patients with type 2 diabetes mellitus with sleep disorders.” Read article here.
