Summary:
In patients with diabetic erectile dysfunction (ED), high-activity placenta-derived mesenchymal stem cells (hPMSCs) combined with low-intensity extracorporeal shock wave therapy (LI-ESWT) significantly improved erectile function compared to patients receiving standard care or placebo,
though it was associated with minor discomfort at the injection site.
| PICO | Description |
|---|---|
| Population | Male patients diagnosed with diabetic erectile dysfunction (N = study participants as per the source). |
| Intervention | Combination of high-activity placenta-derived mesenchymal stem cells (hPMSCs) with low-intensity extracorporeal shock wave therapy (LI-ESWT). |
| Comparison | Standard care or placebo control involving either no treatment or sham procedures. |
| Outcome | The combined therapy of hPMSCs and LI-ESWT significantly enhanced erectile function, demonstrated by improvements in erection duration and penile hardness. It showed a synergistic effect compared to standard care or placebo, with minimal adverse effects reported (e.g., minor discomfort at the injection site). |
Source: Yun-Hua Ji, et al. “High-activity placenta-derived mesenchymal stem cells combined with low-intensity extracorporeal shock wave therapy for diabetic erectile dysfunction: a prospective randomized controlled trial.” Read article here.