Summary:
In patients with diabetic erectile dysfunction, high-activity placenta-derived mesenchymal stem cells (hPMSCs) combined with low-intensity extracorporeal shock wave therapy (LI-ESWT)
significantly improved erectile function, prolonged erection duration, and enhanced penile hardness compared to no treatment or monotherapy with either hPMSCs or LI-ESWT,
though it was associated with no significant adverse effects.
| PICO | Description |
|---|---|
| Population | Adult male patients with diabetic erectile dysfunction (ED). |
| Intervention | High-activity placenta-derived mesenchymal stem cells (hPMSCs) combined with low-intensity extracorporeal shock wave therapy (LI-ESWT). |
| Comparison | Untreated patients or those receiving monotherapy with either hPMSCs or LI-ESWT individually. |
| Outcome | The combination of hPMSCs and LI-ESWT significantly improved erectile function, increased erection duration, and enhanced penile hardness. The therapy was well-tolerated with no significant reported adverse effects. This combined approach demonstrates synergy and is a promising treatment for diabetic ED. |
Source: Yun-Hua Ji, et al. “High-activity placenta-derived mesenchymal stem cells combined with low-intensity extracorporeal shock wave therapy for diabetic erectile dysfunction: a prospective randomized controlled trial.” Read article here.
