Curated, continually updated maps of the trials that shaped diabetes, cardiovascular, and metabolic practice. Each guide links concise PICO summaries with expert commentary — built for clinicians who need the key evidence fast.
By area
- Diabetes: The Landmark Trials — DCCT, UKPDS, ACCORD/ADVANCE/VADT, Steno-2, DPP, and more.
- Cardiovascular Outcomes — the statin trials, SGLT2 and GLP-1 cardiovascular evidence, cardio-renal protection.
- Obesity & Metabolism — SCALE, STEP, SURMOUNT, Look AHEAD, and fatty-liver evidence.
- Endocrinology: Evidence by Topic — thyroid, adrenal and pituitary, reproductive, and bone disorders.
By drug class
- GLP-1 Receptor Agonists — LEADER, SUSTAIN-6, SELECT, STEP, SURMOUNT, FLOW.
- SGLT2 Inhibitors — EMPA-REG, DAPA-HF, EMPEROR-Reduced, CREDENCE, DAPA-CKD.
Prefer to browse? See all PICO summaries or the Landmark Trials archive.
Hormone Insight summaries are reviewed by a practicing endocrinologist and are for healthcare professionals. They summarise published evidence and do not constitute medical advice. See our Editorial Guidelines.