Summary:
In Indian children with type 1 diabetes mellitus (T1DM), prebiotic intervention significantly modulated beneficial gut bacteria, particularly short-chain fatty acid (SCFA)n producing species, without altering glycemic control compared to placebo/control, though it was associated with no major side effects reported.
| PICO | Description |
|---|---|
| Population | Indian children diagnosed with type 1 diabetes mellitus (T1DM). |
| Intervention | Dietary prebiotic supplementation aimed at modulating gut microbiome composition. |
| Comparison | Placebo or control group not receiving prebiotic intervention. |
| Outcome | Significant modulation of beneficial SCFA-producing gut bacteria without changes in glycemic control; intervention was well-tolerated with possible long-term metabolic and anti-inflammatory benefits suggested. |
Source: Vaishali Tamahane, et al. “Effect of prebiotic intervention on glycemic control and gut microbiome profile in Indian children with type 1 diabetes mellitus (T1DM): a pilot randomised control trial.” Read article here.
