Summary:
In Chinese middle-aged and elderly adults with prediabetes or early diabetes, purified anthocyanin supplementation (160, 320, and 640 mg/day for 12 weeks) showed no significant improvement compared to placebo, and it was not associated with adverse effects.
| PICO | Description |
|---|---|
| Population | Chinese middle-aged and elderly adults (n=184) with prediabetes or early-stage diabetes (dysglycemia). |
| Intervention | Daily supplementation with purified anthocyanins at doses of 160 mg, 320 mg, or 640 mg for 12 weeks. |
| Comparison | Placebo group receiving no active anthocyanin supplementation. |
| Outcome | No significant changes or dose-response effects in arterial stiffness (measured by baPWV), blood pressure, ABI, or composite cardiovascular risk indicators were observed after 12 weeks of ACN supplementation. |
Source: Liu, Zhaomin, et al. “Purified Anthocyanins Indicated No Significant Effect on Arterial Stiffness, Four-Limb Blood Pressures and Cardiovascular Risk—A 12-Week Dose-Response Trial in Chinese Middle-Aged and Elderly Adults with Hyperglycemia.” Nutrients. Read article here.
