Summary:
In patients with type 2 diabetes and HbA1c <7.5%, AntiAGE-Biom probiotic supplementation significantly improved body composition, including increased skeletal muscle mass and reduced fat percentage, particularly in men and those with higher baseline HbA1c compared to placebo, though it was associated with no reported adverse effects.
| PICO | Description |
|---|---|
| Population | Adults diagnosed with type 2 diabetes mellitus (T2D), with stable antidiabetic therapy and HbA1c less than 7.5%. |
| Intervention | Daily administration of AntiAGE-Biom probiotic for 3 months in addition to ongoing antidiabetic therapy. |
| Comparison | Placebo treatment under the same clinical conditions, with no additional active probiotic. |
| Outcome | The probiotic group showed a non-significant trend toward decreased HbA1c. Significant improvements were observed in body composition, particularly fat reduction and increased skeletal muscle mass in men and patients with baseline HbA1c ≥ 6.5%. No adverse effects were reported. |
Source: E A Shestakova, et al. “The effect of AntiAGE-Biom probiotic on metabolic features in individuals with type 2 diabetes.” Read article here.
