Summary:
In patients with coronary stenosis proximal to myocardial bridge (MB), intravascular ultrasound (IVUS)-guided stent implantation significantly reduced major adverse cardiac events (MACE), improved stent positioning, and minimized lesion miscoverage and MB intrusion compared to angiography-guided stent implantation, though it was associated with no reported increase in adverse effects.
| PICO | Description |
|---|---|
| Population | Adults (n=117) diagnosed with coronary artery stenosis located proximal to a myocardial bridge (MB). |
| Intervention | IVUS-guided stent implantation (IGSI), enabling real-time vascular imaging for accurate stent placement. |
| Comparison | Angiography-guided stent implantation (AGSI), guided solely by fluoroscopic imaging without adjunctive IVUS. |
| Outcome | IGSI resulted in significantly fewer MACE at 12 months (5.4% vs. 18.0%, P<.05), with improved stent positioning (100% accurate vs. 50.91% mispositioned in AGSI), no stent extension into MB (vs. 32.73% in AGSI), and complete lesion coverage in all cases. Kaplan-Meier and Cox analysis confirmed better outcomes in IGSI group. |
Source: Jia, Shengqi, et al. “IVUS guiding optimize the outcome of intervention of coronary atherosclerotic stenotic lesions proximal to myocardial bridge.” Medicine (Baltimore), 2025 Oct 24;104(43):e45155. Read article here.
