Summary:
In middle-aged and older adults with Type 2 Diabetes (T2D), citrulline supplementation (CITS)
significantly improved microvascular endothelial function, muscle microvascular reactivity, and calf muscle strength compared to no supplementation, though it was associated with minimal adverse effects.
| PICO | Description |
|---|---|
| Population | Middle-aged and older adults diagnosed with Type 2 Diabetes (T2D). |
| Intervention | Citrulline supplementation (CITS). |
| Comparison | No citrulline supplementation. |
| Outcome | CITS significantly improved microvascular endothelial function, muscle microvascular reactivity, and calf muscle strength compared to the control group. Minimal adverse effects were observed with the intervention. |
Source: Figueroa, Arturo, et al. “Citrulline Supplementation Improves Microvascular Function and Muscle Strength in Middle-Aged and Older Adults with Type 2 Diabetes.” Read article here.
