Summary:
In men with Type 2 diabetes mellitus, combined structured exercise training and broccoli sprout supplementation significantly improved apolipoprotein profiles and metabolic markers compared to exercise or supplementation alone or no intervention, though it was associated with no reported adverse effects.
| PICO | Description |
|---|---|
| Population | Forty-four adult males diagnosed with Type 2 diabetes mellitus. |
| Intervention | A 12-week combination of structured aerobic and resistance training (3 sessions/week at 60–70% 1RM/VO₂peak) plus 10 g/day of broccoli sprout supplementation taken after meals. |
| Comparison | Control group (no intervention); Training only group; Supplementation only group. |
| Outcome | The combined group exhibited the greatest improvements: ApoA-I increased (+44.92 ± 6.05 mg/dL), ApoB-100 decreased (-48.30 ± 7.20 mg/dL), ApoJ decreased (-44.05 ± 5.76 mg/dL), as well as significant reductions in glucose, insulin, and HOMA-IR. Large effect sizes suggest an additive benefit, primarily driven by exercise. |
Source: Maryam Delfan, et al. “Combined Effects of Exercise and Broccoli Supplementation on Metabolic and Lipoprotein Biomarkers in Adults with Type 2 Diabetes: A Randomized Controlled Trial.” Read article here.
