Summary:
In people with prediabetes, a diet rich in fermentable carbohydrates combined with metformin
significantly improved glycaemic control and reshaped the gut microbiota compared to metformin alone, though it was associated with gastrointestinal side effects.
| PICO | Description |
|---|---|
| Population | Adults with prediabetes. |
| Intervention | A diet rich in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) combined with metformin. |
| Comparison | Metformin alone without the dietary intervention. |
| Outcome | The combination of a FODMAP-rich diet with metformin significantly enhanced glycaemic control and showed a beneficial impact on gut microbiota composition. However, gastrointestinal side effects were reported. |
Source: Chu, Natural H S, et al. “Combining a diet rich in fermentable carbohydrates with metformin improves glycaemic control and reshapes the gut microbiota in people with prediabetes.” Read article here.
