Summary: In patients with type 2 diabetes mellitus and cognitive impairment, moxibustion at different temperatures (particularly 44–46 ℃) significantly improved cognitive function and stabilized blood glucose levels compared to moxibustion at other temperatures. PICO Description Population Patients with type 2 diabetes mellitus and cognitive impairment Intervention Moxibustion at different temperatures, notably 44–46 ℃ over 2–3 months Comparison Moxibustion at other temperature ranges Outcome Improved cognitive function and stabilized average blood glucose; adverse events not reported Source: Yan Wei, et al. “Moxibustion at different temperatures for cognitive impairment in type 2 diabetes mellitus: a randomized controlled trial.” Read article here.
Author: FWA
Summary: In patients with carpal tunnel syndrome (CTS), ultrasound-guided corticosteroid injection combined with acupotomy release of the transverse carpal ligament significantly improved symptom relief and functional recovery compared to corticosteroid injection alone, though it was associated with no reported complications. PICO Description Population Patients diagnosed with carpal tunnel syndrome (CTS); 68 participants randomly assigned and treated from January 2023 to June 2024. Intervention Ultrasound-guided corticosteroid injection combined with acupotomy release of the transverse carpal ligament (Group A). Comparison Ultrasound-guided corticosteroid injection alone (Group B). Outcome Group A showed significantly better symptom severity (BCTQ-S) and function (BCTQ-F) scores at 1 and…
Summary: In adults with type 2 diabetes, tirzepatide treatment (15 mg weekly) significantly reduced HbA1c and maintained counterregulatory glucagon response during induced hypoglycemia compared to placebo, though it was associated with delayed cortisol and noradrenaline responses and reduced hypoglycemic symptom scores. PICO Description Population Adults with type 2 diabetes (N=42) undergoing hypoglycemic clamp procedures in a randomized, double-blind, crossover study. Intervention Tirzepatide 15 mg administered once weekly for 12 weeks before hypoglycemic clamp testing. Comparison Placebo administered for 12 weeks in a crossover design, with an 8–10 week wash-out period between treatments. Outcome Tirzepatide significantly reduced HbA1c (-1.5% vs. +0.5%…
Summary: In patients with type 2 diabetes, flaxseed oil supplementation (FOS) did not lead to statistically significant differences in a cluster of seven measures, including abdominal obesity, hypertension, platelet hyperaggregability, hyperglycemia, and dyslipidemia, based on apolipoprotein E genotypes. PICO Description Population Patients with type 2 diabetes. Intervention Flaxseed oil supplementation (FOS). Comparison Evaluations based on apolipoprotein E genotypes. Outcome No statistically significant differences were noted in a cluster of seven measures: abdominal obesity, hypertension, platelet hyperaggregability, hyperglycemia, and dyslipidemia among different apolipoprotein E genotypes. Source: Douglas E Barre, et al. “Thus far there are no statistically significant differences between various…
Structured Summary: In patients with type 2 diabetes mellitus (T2DM) and metabolic-associated steatotic liver disease (MASLD), a high dietary fiber cereal meal intervention significantly improved liver fibrosis and glycemic control compared to the control group with a lower dietary fiber intake, though it was associated with no significant change in BMI, potentially due to increased caloric intake from the fiber. PICO Description Population Patients with type 2 diabetes mellitus (T2DM) and metabolic-associated steatotic liver disease (MASLD). Intervention High dietary fiber cereal meal intervention, with 24g daily fiber intake. Comparison Control group with lower dietary fiber intake (<10g daily). Outcome High…
Summary: In individuals with type 2 diabetes, aquatic exercise significantly improved blood pressure and functional capacity over time compared to control groups, without changes in analyzed parameters, though it was associated with no notable adverse effects. PICO Description Population Adults diagnosed with type 2 diabetes. Intervention A five-week aquatic exercise protocol focusing on improving blood pressure, respiratory function, and functional capacity. Comparison Control groups with no intervention over the same time period. Outcome Aquatic exercise reduced systolic and diastolic blood pressure and improved functional capacity over time. However, no significant differences were observed when compared to control groups in the…
Summary: In men with Type 2 diabetes mellitus (T2DM),combined exercise training and broccoli sprout supplementation significantly improved Apolipoprotein A-I levels and reduced Apolipoprotein B-100 levels and other metabolic markers compared to control, supplementation-only, or training-only groups, though it was associated with no reported adverse effects. PICO Description Population Adult males with Type 2 diabetes mellitus (T2DM). Intervention Combined exercise training and broccoli sprout supplementation (10 g/day for 12 weeks). Comparison Control group, broccoli sprout supplementation-only group, and exercise training-only group. Outcome Significant improvement in Apolipoprotein A-I levels and reduction in Apolipoprotein B-100 levels, along with favorable changes in metabolic and…
Summary: In patients with chronic high-altitude disease (CHAD), hydrogen-rich water (HRW) supplementation for 60 days significantly downregulated inflammation- and cytokine-related gene pathways compared to placebo water (PW), though it was associated with a non-significant downward trend in oxidative stress and inflammation markers, and no major side effects reported. PICO Description Population Adults diagnosed with chronic high-altitude disease (CHAD); n = 50 enrolled, 43 completed (HRW group, n = 23; PW group, n = 20). Intervention Daily intake of hydrogen-rich water (HRW) over a 60-day period. Comparison Daily intake of placebo water (PW) over the same 60-day period. Outcome HRW supplementation…
Summary: In patients undergoing laparoscopic living-donor nephrectomy, erector spinae plane (ESP) block combined with routine analgesia significantly reduced total tramadol consumption compared to routine postoperative analgesic treatment alone, though it was associated with no significant difference in pain scores within the first 24 hours postoperatively. PICO Description Population Adult donors (n=60) scheduled for elective laparoscopic living-donor nephrectomy at a transplant center. Intervention Bilateral erector spinae plane block under ultrasonographic guidance, in addition to standard postoperative analgesia. Comparison Standard postoperative analgesic protocol without nerve block (control group). Outcome No significant differences in verbal numerical or Wong-Baker Faces Pain Rating Scale scores…
Summary: In patients with chronic coronary syndrome, a 12-week hybrid Tai Chi cardiac rehabilitation programme (TCCRP) significantly reduced perceived psychological stress and oxidative stress markers compared to a conventional exercise cardiac rehabilitation programme (CECRP), three sessions per week for 12 weeks, though it was associated with no reported adverse effects. PICO Description Population Adults diagnosed with chronic coronary syndrome (CCS), undergoing cardiac rehabilitation while continuing routine drug treatments. Intervention A 12-week hybrid Tai Chi cardiac rehabilitation programme (TCCRP), conducted three times weekly. Comparison A 12-week conventional exercise cardiac rehabilitation programme (CECRP), also conducted three times weekly. Outcome TCCRP significantly decreased…