Clinical Context Randomized controlled trials establish efficacy under ideal conditions, but real-world effectiveness may differ due to patient selection, adherence…
Browsing: PICO
Clinical Context Type 2 diabetes is paradoxically associated with increased fracture risk despite often-normal or even elevated bone mineral density…
Clinical Context Diabetic foot ulcers (DFUs) affect approximately 15-25% of people with diabetes during their lifetime and are the leading…
Clinical Context Perioperative hyperglycemia and glucose variability are independent predictors of poor outcomes after cardiac surgery, including increased mortality, sternal…
Clinical Context Pediatric type 1 diabetes management remains challenging despite advances in technology. While continuous glucose monitoring (CGM) provides unprecedented…
Summary: In adults with persistent and recalcitrant diabetic foot ulcers that failed to heal with conventional treatment, full-thickness decellularized placental…
Clinical Context Prediabetes affects approximately 96 million American adults, with global prevalence estimates exceeding 500 million. The condition represents a…
Clinical Context Chronic low-grade inflammation is increasingly recognized as a key driver of metabolic disease. In obesity and prediabetes, adipose…
Clinical Context Chronic low-grade inflammation is increasingly recognized as a central driver of metabolic disease progression. In obesity and prediabetes,…
Clinical Context Cognitive decline and dementia represent enormous public health challenges, with limited effective treatments available. The MIND diet (Mediterranean-DASH…