Clinical Context GLP-1 receptor agonists have demonstrated effects beyond glucose lowering: anti-inflammatory properties (reducing CRP, IL-6, TNF-α), neuroprotective effects (shown…
Browsing: PICO
Clinical Context Hypoglycemia remains the major limiting factor in achieving tight glycemic control in type 1 diabetes. The normal counterregulatory…
Summary: In pregnant individuals with obesity classified as metabolically healthy obese (MHO) or metabolically unhealthy obese (MUO), intensive behavioral therapy…
Summary: In adults with obesity and osteoarthritis awaiting elective hip or knee arthroplasty, the Flinders Program of self-management support (a…
Clinical Context Pituitary adenomas are the third most common intracranial tumor, affecting up to 20% of the population based on…
Summary: In adults undergoing laparoscopic sleeve gastrectomy (LSG) for obesity and metabolic disorders, a preoperative predictive nomogram combining HDL-C levels…
Clinical Context First-degree relatives of individuals with premature coronary heart disease (CHD before age 55 in men, 65 in women)…
Clinical Context Metabolic flexibility—the body’s ability to switch between carbohydrate and fat oxidation based on nutrient availability and energy demands—is…
Summary: In 90 male patients with diabetes mellitus-induced erectile dysfunction and TCM diagnosis of qi deficiency with blood stasis syndrome,…
Summary: In 100 male patients with type 2 diabetes mellitus, TCM qi-yin deficiency syndrome, and asthenospermia (progressive motility <32%), Wuziyuye…