Summary: In 126 pregnant women with type 1 diabetes, metformin (titrated to 1000 mg twice daily) as adjunct to standard…
Browsing: PICO
Clinical Context Patients with diabetes undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) face a therapeutic dilemma: they have…
Clinical Context The transition from pediatric to adult diabetes care represents one of the most vulnerable periods for young people…
Summary: In adults with HFpEF (EF ≥50%), obesity (BMI ≥30 kg/m²), stratified by presence or absence of type 2 diabetes…
Clinical Context Heart failure with preserved ejection fraction (HFpEF) represents approximately half of all heart failure cases and has proven…
Clinical Context Type 2 diabetes requires sustained self-management: daily medication adherence, dietary modification, physical activity, and glucose monitoring. Many patients…
Clinical Context SGLT2 inhibitors have transformed type 2 diabetes management, offering glycemic control alongside weight loss, blood pressure reduction, and…
Clinical Context SGLT2 inhibitors have demonstrated remarkable cardiovascular benefits in large outcome trials, reducing heart failure hospitalizations and cardiovascular death…
Clinical Context Ischemic heart disease remains the leading cause of death worldwide, and LDL cholesterol reduction is the cornerstone of…
Clinical Context Gestational diabetes mellitus (GDM) requires intensive management during a brief but critical window—typically 12-16 weeks from diagnosis to…