Summary:
In patients with periodontitis and type 2 diabetes mellitus (T2DM), periodontal therapy
significantly improved clinical parameters such as probing depth (PD), clinical attachment level (CAL), and plaque index (PI) compared to patients with higher baseline markers of PD, CAL, PI, or HbA1c levels, though it was associated with the need to carefully consider nine baseline factors for optimal predictability in therapy outcomes.
| PICO | Description |
|---|---|
| Population | Patients with type 2 diabetes mellitus (T2DM) and periodontitis. |
| Intervention | Periodontal therapy considering baseline factors (such as PD, CAL, PI, HbA1c, and more). |
| Comparison | Patients with higher baseline levels of PD, CAL, PI, or HbA1c had worse outcomes compared to those with lower levels. |
| Outcome | Periodontal therapy led to better outcomes at 6 months, as indicated by reductions in PD, CAL, PI, and HbA1c levels. However, nine baseline patient factors need to be considered for accurate predictability of treatment success. |
Source: Nidia Castro Dos Santos, et al. “Factors influencing the response to periodontal therapy in patients with diabetes: post hoc analysis of a randomized clinical trial using machine learning.” Read article here.
