Summary:
In patients undergoing elective transsphenoidal surgery for pituitary adenoma, a pure endoscopic approach significantly reduced the risk of tumor recurrence and enhanced long-term achievement of surgical goals and anterior pituitary function compared to an endoscope-assisted microscopic technique, though it was associated with similar complication rates and no increase in hospital stay or other morbidities.
| PICO | Description |
|---|---|
| Population | Patients (n=33) undergoing elective transsphenoidal surgery for pituitary adenoma. |
| Intervention | Pure endoscopic transsphenoidal surgery for pituitary adenoma resection. |
| Comparison | Endoscope-assisted microscopic transsphenoidal surgery. |
| Outcome | Endoscopic surgery resulted in lower risk of tumor recurrence (OR = 0.24), better long-term achievement of surgical goals (OR = 3.80), and improved anterior pituitary function (OR = 1.60). No significant differences were found in complications, hospital stay, visual and olfactory outcomes, or rates of DI/SIADH. |
Source: Márton Eördögh, et al. “Comparison of endoscopic and endoscope-assisted microscopic transsphenoidal surgery for pituitary adenoma resection: a prospective randomized study.” Read article here.
