Summary: In adults with chronic hypoparathyroidism requiring conventional therapy with calcium and active vitamin D, TransCon PTH (palopegteriparatide) once daily…
Browsing: PICO
Clinical Context The concept of type 2 diabetes “remission”—achieving normal glycemia without diabetes medications—has been revolutionized by intensive dietary intervention…
Summary: In adults with chronic kidney disease (eGFR ≥25, UACR 30-3,500 mg/g) and overweight/obesity (BMI ≥27) without diabetes, semaglutide 2.4…
Clinical Context Diabetic foot ulcers (DFUs) are traditionally managed with wound care, offloading, infection control, and vascular optimization. Exercise is…
Clinical Context Radioactive iodine (RAI) ablation is a cornerstone of differentiated thyroid cancer (DTC) management following total thyroidectomy. Effective RAI…
Clinical Context The GLP-1 receptor agonist class has transformed type 2 diabetes management, with semaglutide emerging as a particularly effective…
Clinical Context Sleep deprivation has reached epidemic proportions in modern society, with many adults routinely sleeping less than the recommended…
Summary: In healthy adult volunteers (Japanese n=20-21, non-Japanese n=20-21), single-dose cilofexor 100 mg or firsocostat 20 mg showed higher plasma…
Clinical Context Diabetic kidney disease (DKD) remains the leading cause of end-stage renal disease worldwide, affecting approximately 40% of patients…
Clinical Context Prediabetes affects approximately 96 million American adults—more than one-third of the adult population—and represents a critical window for…