Summary:
In patients with type 2 diabetes and a history of prior stroke, intensive systolic blood pressure (SBP) control significantly reduced cardiovascular outcomes compared to standard SBP control,
though it was associated with a higher rate of adverse events, including hypotension and electrolyte imbalances.
| PICO | Description |
|---|---|
| Population | Patients with type 2 diabetes and a history of prior stroke enrolled in the ACCORD-BP trial. |
| Intervention | Intensive systolic blood pressure control targeting a systolic BP of <120 mmHg. |
| Comparison | Standard systolic blood pressure control targeting a systolic BP of <140 mmHg. |
| Outcome | Intensive SBP control significantly reduced major adverse cardiovascular events, but resulted in a higher incidence of adverse events, including hypotension and electrolyte disturbances. |
Source: Zhixian Wang, et al. “Intensive Blood Pressure Control in Patients With Diabetes and Previous Stroke: A Post-Hoc Analysis of ACCORD-BP Trial.” Read article here.
