Summary:
In patients requiring extraction of single-rooted teeth, alveolar ridge preservation using titanium-prepared platelet-rich fibrin (T-PRF) significantly enhanced ridge dimensional maintenance, increased bone density, improved soft tissue healing, and reduced post-operative pain compared to leukocyte and platelet-rich fibrin (L-PRF) and spontaneous healing, though it was associated with no reported adverse effects.
| PICO | Description |
|---|---|
| Population | Adults undergoing atraumatic flapless extraction of single-rooted teeth for whom alveolar ridge preservation may be indicated prior to implant placement. |
| Intervention | Alveolar ridge preservation using titanium-prepared platelet-rich fibrin (T-PRF). |
| Comparison | Alveolar ridge preservation with leukocyte and platelet-rich fibrin (L-PRF), and spontaneous healing without intervention. |
| Outcome | T-PRF resulted in significantly better preservation of ridge width, height, and bone density (P = 0.000), improved soft-tissue healing and keratinized tissue width (P < 0.05), and lower pain scores and analgesic use (P = 0.000 and P < 0.05 respectively). It also reduced the need for bone regeneration at implant placement compared to controls. |
Source: Emad Aldden Aldommari, et al. “Titanium-prepared platelet-rich fibrin enhances alveolar ridge preservation: a randomized controlled clinical and radiographic study.” Read article here.
