Summary:
In patients with mandibular Class II furcation defects, treatment with platelet rich fibrin matrix (PRFM) membrane combined with demineralized freeze-dried bone allograft (DFDBA) significantly enhanced clinical and radiographic outcomes compared to collagen membrane (Colo Gide) combined with DFDBA, though it was associated with no complete defect closure in either group.
| PICO | Description |
|---|---|
| Population | 24 adult patients (15 males, 9 females) presenting with mandibular Class II furcation defects (buccal or lingual). |
| Intervention | Platelet rich fibrin matrix (PRFM) membrane used in combination with demineralized freeze-dried bone allograft (DFDBA). |
| Comparison | Collagen membrane (Colo Gide) used in combination with demineralized freeze-dried bone allograft (DFDBA). |
| Outcome | Higher rate of improvement from Class II to Class I furcation (83.33% in PRFM group vs. 66.66% in collagen group); greater reduction in horizontal defect depth; no complete defect closure observed in either group. |
Source: Dr Chitrika Subhadarsanee, et al. “Comparative evaluation of platelet rich fibrin matrix (PRFM) membrane and collagen membrane with demineralized freeze-dried bone allograft (DFDBA) in the treatment of mandibular class II furcation defects: A randomized controlled trial.” Read article here.
