Summary:
In older adults aged 65–85 with overweight or obesity, the MIND diet significantly improved global cognitive scores compared to a control diet, though it was associated with no reported adverse effects. The effect was significant only among individuals with a body mass index (BMI) ≥ 35 kg/m2.
| PICO | Description |
|---|---|
| Population | Community-dwelling older adults aged 65–85 years with overweight or obesity (mean BMI = 33.9 kg/m²); N = 604. |
| Intervention | The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet over multiple years, assessing annual cognitive change. |
| Comparison | Control diet in a randomized trial setting, matched for calorie content and frequency of support contact. |
| Outcome | Only among participants with BMI ≥ 35 kg/m² (n = 213), the MIND diet was associated with significantly higher global cognitive scores (+0.040 standardized units/year, SE = 0.017, p = 0.018); no significant effects observed in participants with lower BMI. |
Source: Halloway, Shannon, et al. “Effect modifiers of the MIND diet for cognition in older adults: The MIND diet trial.” Read article here.
