Summary:
In adults at risk of type 2 diabetes with achieved weight loss, intermittent fasting combined with early time-restricted eating and calorie restriction significantly reduced systemic and adipose tissue markers of inflammation compared to control or other weight loss methods,
though it was associated with no differential impact on inflammatory markers when weight loss exceeded median.
| PICO | Description |
|---|---|
| Population | Adults at risk of type 2 diabetes undergoing weight loss interventions. |
| Intervention | Intermittent fasting combined with early time-restricted eating and calorie restriction. |
| Comparison | Control groups and other forms of weight loss interventions without intermittent fasting or time-restricted eating. |
| Outcome | Achieved weight loss led to reductions in systemic and adipose tissue inflammatory markers; however, the type of weight loss intervention did not differentially impact inflammatory markers among participants with weight loss above the median. |
Source: Laurent Turner, et al. “Impact of Achieved Weight Loss by Intermittent Fasting Plus Early Time-Restricted Eating and Calorie Restriction on Systemic and Adipose Tissue Markers of Inflammation in Adults at Risk of Type 2 Diabetes: An Exploratory Sub-Study.” Read article here.
