Summary:
In individuals with type 2 diabetes and normal BMI, a three-month Chinese Medical Nutrition Therapy (CMNT) involving intermittent energy restriction significantly maintained diabetes remission over three years compared to no intervention (control group), though it was associated with no major reported side effects.
| PICO | Description |
|---|---|
| Population | Adults with type 2 diabetes who attained diabetes remission and a normal BMI (below 24 kg/m²) through an initial dietary intervention. |
| Intervention | Three-month CMNT consisting of six cycles of five days of 840 kcal/day energy restriction followed by ten days of ad libitum eating, followed by 3 years of self-guided diet per national guidelines. |
| Comparison | Control group with no dietary intervention or active follow-up beyond standard care. |
| Outcome | After 3 years, 75% of the CMNT group maintained diabetes remission versus 0% in the control group. The remission was positively associated with withdrawal from insulin or insulinotropic agents. Participants also showed fewer complications, hospitalizations, and improved quality of life. |
Source: Wu, Ruiyu, et al. “Maintained diabetes remission among normal BMI individuals achieved without ongoing intervention: a three-year follow-up study of intermittent calorie restriction.” Read article here.
