Summary:
In patients with diabetic neuropathic pain (DNP), non-invasive peripheral nerve neuromodulation (NipRF therapy) significantly reduced neuropathic pain symptoms compared to placebo/sham treatment, though it was associated with minimal adverse events and was well tolerated.
| PICO | Description |
|---|---|
| Population | Adults diagnosed with diabetic neuropathic pain (DNP), experiencing chronic peripheral neuropathic symptoms related to diabetes mellitus. |
| Intervention | Non-invasive peripheral nerve radiofrequency (NipRF) neuromodulation therapy administered according to the study protocol. |
| Comparison | Placebo or sham treatment without active neuromodulation. |
| Outcome | NipRF therapy significantly reduced neuropathic pain scores compared to placebo, with improved functional outcomes and quality of life. The intervention demonstrated a favorable safety profile with minimal adverse events. |
Source: Genç Perdecioğlu, Gevher Rabia, et al. “Non-invasive peripheral nerve neuromodulation in diabetic neuropathic pain: A randomised controlled trial.” Read article here.
