Summary:
In overweight prediabetic individuals, GOS milk supplemented with mulberry leaf and corn silk extracts significantly reduced 1-hour postprandial glucose, maximum glucose levels, and overall 2-hour glucose excursion compared to pure milk, though it was associated with no reported side effects.
| PICO | Description |
|---|---|
| Population | Prediabetic adult individuals (n=11), including a subgroup of overweight participants. |
| Intervention | Milk-based interventions containing mulberry leaf and corn silk extracts, particularly galacto-oligosaccharide (GOS) milk supplemented with these extracts. |
| Comparison | Pure milk, lactose-hydrolyzed milk, and lactose-hydrolyzed milk with mulberry leaf, corn silk, and resistant dextrin. |
| Outcome | In the overweight subgroup, GOS milk with mulberry and corn silk significantly reduced 1-hour postprandial glucose (-0.84 mmol/L), maximum PG (-0.54 mmol/L), and glucose excursion at 2 hours (-0.62 mmol/L), with no adverse events reported. |
Source: You Sun, et al. “Effects of Mulberry Leaf and Corn Silk Extracts Against α-Amylase and α-Glucosidase In Vitro and on Postprandial Glucose in Prediabetic Individuals: A Randomized Crossover Trial.” Read article here.
