Summary:
In overweight or obese adults with prediabetes, a combined intervention of concurrent training and microencapsulated persimmon–karonda polyphenol supplementation significantly improved glycemic control, reduced inflammatory markers, enhanced physical fitness, and improved psychological well-being compared to placebo, exercise alone, or supplementation alone, though it was associated with no reported adverse effects.
| PICO | Description |
|---|---|
| Population | Adults with prediabetes who were overweight or obese (n=43). |
| Intervention | Eight weeks of concurrent training (CBT) combined with supplementation of a microencapsulated persimmon–karonda polyphenol formulation (EATME). |
| Comparison | Placebo, CBT alone, or EATME alone. |
| Outcome | The combined intervention group (CBT + EATME) showed the greatest improvements in fasting blood glucose (p < 0.01), HbA1c (p < 0.05), insulin resistance (HOMA-IR, p < 0.01), reduction in inflammatory markers (hs-CRP and IL-6, both p < 0.01), increased adiponectin (p < 0.01), improved V̇O2max and muscular strength (both p < 0.05), and enhanced psychological well-being compared to placebo. |
Source: Sukatta, Udomlak, et al. “Synergistic Effects of Microencapsulated Polyphenols and Concurrent Training on Metabolic Health and Fitness in Overweight/Obese Adults with Prediabetes.” Read article here.
